Abstract: GLM-4.5 marks a significant milestone in the evolution of large models, from breakthroughs in capability to broad industrial deployment. Its core innovation lies in achieving native multimodal integration and native agentic collaboration. By unifying reasoning, coding, and agentic capabilities at the foundational level, the model undergoes a comprehensive advancement in understanding, generation, and reasoning. At the application level, building upon GLM-4.5, we have developed an open API and agent ecosystem, facilitating a paradigm shift from “model invocation” to “application co-creation.” GLM-4.5 has been widely adopted across sectors such as education, scientific research, manufacturing, and government services.